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Key Dependence articles by category
PharmacologyClick to expand category
Mu opioid partial agonist and Kappa opioid antagonist
High affinity for Mu opioid receptors
Slow receptor dissociation kinetics
Low physical dependence liability
Human PharmacokineticsClick to expand category
Sublingual absorption and time to peak effect
Plasma levels and withdrawal symptoms
Clinical PharmacologyClick to expand category
Low physical dependence liability
Blockade of opioid agonist effects
Ceiling to cardiovascular and respiratory effects
Agonist/antagonist effects of buprenorphine and buprenorphine/naloxone combination
Effects of buprenorphine in dually dependent opioid/cocaine individuals
Clinical StudiesClick to expand category
Placebo controlled
Dose rising with ‘active’ placebo
Comparison with methadone
Less than daily dosing schedules
Withdrawal/detoxification
Transfer to naltrexone
Special patient groups
In use experience
Key Veterinary articles by category
VeterinaryClick to expand category
Veterinary